Chicken and Zucchini Casserole

This Chicken and Zucchini Casserole with stuffing is a creamy, comforting dinner perfect for busy weeknights. Made with tender chicken, fresh zucchini, and a buttery stuffing topping, this old-fashioned casserole is an easy family favorite that's great for using up summer zucchini or rotisserie chicken.

This Chicken and Zucchini Casserole is always in our dinner rotation right alongside favorites like my Chicken and Rice Casserole, Chicken Bacon Ranch Casserole, and Chicken Stuffing Casserole. It's a great way to use up fresh summer zucchini or squash, plus it comes together easily with simple ingredients and leftover or rotisserie chicken.

Why We Keep Coming Back to This Recipe

• The buttery stuffing topping gets perfectly golden and crisp in the oven, just like in my Stuffing Topped Chicken Pot Pie
• This easy dinner is a great way to use up fresh zucchini without feeling like "just another veggie dinner"
• Rotisserie chicken makes this casserole super easy on busy nights
• Creamy, comforting, and one of those dinners everybody goes back for seconds of

Ingredient Notes

Using simple, shortcut ingredients, this Chicken and Zucchini Casserole comes together quickly and can be ready for the oven in under 10 minutes. See the printable recipe card below for exact ingredient amounts and step-by-step instructions.

• Stuffing Mix: boxed chicken stuffing keeps this casserole quick, easy, and full of flavor while creating that buttery topping everyone loves.
• Medium Zucchini: fresh medium zucchini works best since it becomes tender while baking without getting overly mushy. If your zucchini seems extra watery, lightly pat the slices dry before adding them to the casserole.
• Chicken: cooked and shredded chicken works perfectly here. Rotisserie chicken is one of my favorite shortcuts for busy nights.

Variations

• Swap some of the medium zucchini for yellow squash during summer when you have extra garden veggies on hand.
• Want it extra cheesy? Add shredded mozzarella cheese, Parmesan cheese, or cheddar cheese on top before baking.
• Rotisserie chicken makes this casserole even quicker, but cooked chicken breasts work great too.
• Add a little kick with diced green chiles, red pepper flakes, or pepper jack cheese.
• Diced mushrooms or bell peppers adds extra texture and flavor.
• Cream of mushroom or cream of celery soup can easily be used instead of cream of chicken soup.
• For an even creamier casserole, swap some of the sour cream for cream cheese.
• Try using herb-seasoned stuffing mix for even more flavor.

How to Make Chicken and Zucchini Casserole

This chicken zucchini casserole comes together quickly with simple ingredients and just a few easy steps.

Step 1. Combine the melted butter and stuffing mix together in a large bowl. Scoop 1 cup of the stuffing mixture out and set aside for the buttery topping added later.

Step 2. In the same bowl as the remaining stuffing mixture, add the medium zucchini, onion, cooked chicken, cream of chicken soup, and sour cream. Stir until fully combined.

Step 3. Spread the chicken zucchini mixture into a greased 9×13 baking dish. Sprinkle the reserved stuffing mixture evenly over the top.

Step 4. Place the casserole dish into a preheated 350 degree oven and bake for about 45 minutes, or until hot and bubbly with a golden brown stuffing topping. Remove from oven and serve warm!

Tips for Success

• If your medium zucchini seems watery, pat it dry with paper towels first.
• Rotisserie chicken makes this casserole even easier on busy nights.
• For the best texture, bake until the stuffing topping is golden brown and crisp.
• Let it sit a few minutes before serving so it sets up a bit.
• Feel free to season with salt, black pepper, garlic powder, or onion powder to taste.
• You can grease the baking dish with olive oil or nonstick cooking spray.

Serving Suggestions

Since this casserole already includes chicken and zucchini, it can easily be served as a full meal on its own. However, if your family is anything like mine and loves a few side dishes with dinner, here are some favorites that pair perfectly with it!

• Mashed Potatoes- these garlic mashed potatoes are fluffy, creamy, and packed with flavor. They are a great option to serve on the side, especially since they are quickly made using the Instant Pot.
• Roasted Veggies- you can never have too many vegetables in your dinner, right? Crispy Brussel Sprouts, some roasted seasoned carrots, or even garlic roasted asparagus.
• Fresh Garden Salad- use up the rest of your garden veggies and incorporate them into this meal!
• Bread- my family loves their bread and it offers the perfect addition to this casserole. Pull Apart Garlic Bread is a favorite of ours with this, or even our Garlic Cheese Crescents!

Storage & Make-Ahead

• Refrigerator: Store leftovers in an airtight container in the fridge for up to 4 days.
• Freezer: Let the casserole cool completely, then wrap tightly and freeze for up to 2 months.
• Reheating: Warm individual portions in the microwave or cover the casserole dish with foil and reheat in the oven until warmed through.
• Make Ahead: Assemble the casserole up to 24 hours ahead of time, cover, and refrigerate until ready to bake. You may need to add a few extra minutes to the bake time.

Chicken and Zucchini Casserole Recipe FAQs

More Zucchini Recipes You’ll Love

Tried this recipe? Even kids who normally aren't big zucchini fans tend to enjoy this casserole. Leave a ⭐⭐⭐⭐⭐ rating and let me know what you think in the comments! You can also follow me on Pinterest for even more easy, family-friendly recipes.