Cheesy Mexican Chicken Spaghetti

Cheesy Mexican Chicken Spaghetti is a Tex Mex version of classic Chicken Spaghetti Casserole! A quick and easy casserole perfect for busy weeknights or having guests over! Creamy pasta with shredded chicken, salsa, taco seasoning, shredded cheese, and more! Comfort food at its finest!

 

Cheesy Chicken Spaghetti is one of those classic dinner recipes perfect for any occasion! Simple to make, hearty, and family approved! From the tender pasta, shredded chicken, and incredible Tex Mex sauce, its hard to stop at just one serving! This “stick to your ribs” meal is perfect served with some Garlic Cheese Crescents or Garlic Parmesan Pull Apart Bread!

Why You’ll Love this Easy Mexican Chicken Spaghetti

• Easy to Prepare– with only about 10 minutes of prep needed, this casserole can be oven ready in no time!
• Uses Simple Ingredients– using simple pantry staples, you may already have the needed ingredients on hand!
• Feeds Everyone– since this makes a FULL 9×13, there is plenty for everyone and leftovers are just as yummy!
• Perfect for any Occasion– whether you have a busy weeknight, guests coming over, or signed up to bring someone a meal, this pasta is just the thing to make!

Ingredients Needed for Cheesy Mexican Chicken Spaghetti

See printable recipe card below for exact ingredient amounts and step by step directions.

• Pasta– I use Angel Hair Pasta and have found it works the best. Of course, you can use Spaghetti noodles too though
• Chicken– cooked and shredded or diced. I keep cooked chicken in my freezer for meals like this, but Rotisserie chicken works great too
• Cream of Chicken Soup– since this has a lot of salt in it already, no additional salt is needed in this recipe
• Salsa– I use a medium, chunky salsa, however, you can also use a can of Rotel tomatoes if desired
• Sour Cream– this brings the creaminess to the casserole. You can also use plain Greek yogurt if you don’t have salsa on hand
• Mexican Cheese– shredded, you can also use Colby Jack, Pepper-jack, Cheddar cheese, etc.
• Taco Seasoning– either one packet, or use my homemade recipe for an easy peasy option

Variations

• Chop Bell Peppers and Onions and add to the pasta mixture prior to cooking.
• Add in some diced jalapenos.
• Pour some hot sauce on top just prior to serving.
• Black olives or mushrooms are great additions to the topping or to add into the casserole.
• Use cream of mushroom soup in place of the cream of chicken soup.

How to make Mexican Chicken Spaghetti

1. Preheat oven to 350 degrees and grease a 9×13 inch baking dish with cooking spray.
2. Boil pasta according to package directions on box. Drain water.
3. Stir the cooked pasta, chicken, cream of chicken, salsa, sour cream, 1 cup cheese, and taco seasoning in a bowl.
4. Pour pasta mixture into prepared baking dish.
5. Sprinkle remaining 1/2 cup cheese evenly on top.
6. Cover dish with aluminum foil.
7. Place pan into oven and cook about 25 minutes. Remove from oven and serve!

What to serve with Tex Mex Chicken Spaghetti

This comfort food casserole is already PACKED with flavor, so you don’t need too much to make this a complete meal! Perhaps pair this pasta with some fluffy, homemade biscuits, or cheesy garlic bread! If you want to keep the Tex Mex vibe going, you can also make a skillet of Loaded Cornbread or some refried beans.

How to store leftover Cheesy Mexican Chicken Spaghetti

With so many way to store this casserole, here are the best ways to ensure freshness.

• Refrigerator: store leftovers in an airtight container for up to 4 days.
• Freezer: store leftovers in a freezer safe container for up to 2 months.
• Freezer Meal: to make this into a freezer meal, prepare the casserole as directed but do not bake it. Cover is with saran plastic wrap followed by aluminum foil. Place casserole into the freezer for up to 2 months. Once ready to bake, allow to fully thaw and bake as directed.
• Reheating Leftovers: place serving into microwave and heat until desired temperature is reached.

Frequently Asked Questions

Can raw chicken be used in this creamy chicken spaghetti casserole?

Unfortunately, no! It won’t fully cook once combined with the other ingredients in the time directed and if you increase the time, it’ll dry out the casserole. To save on time, you can use canned chicken or Rotisserie chicken.

What is the difference between this recipe and the classic chicken spaghetti recipe?

The cheesy chicken spaghetti’s are the same, but this version includes salsa and taco seasoning to add a Mexican flair whereas the classic version is creamy and cheesy, but omits the seasoning/salsa.

Can I add in some veggies to this casserole?

Absolutely! I love chopping up bell peppers and onions and adding them in the pasta mixture before I place the casserole into the oven.

Can I make this in a crock pot?

Yes! Combine ingredients as directed in recipe and rather than placing in the oven, you will pour mixture into your slow cooker. Cook on low for about 4 hours or high for about 2 hours. Sprinkle some cheese on top and serve!

More Pasta Recipes to try

Ultimate Chicken Casserole– loaded with flavor! Tender noodles, shredded chicken, bacon, corn, and more!

Bruschetta Chicken Pasta– an easy weeknight dinner full of fresh tomatoes, basil, pasta, balsamic vinegar, and topped with seasoned chicken!!

Chicken Bacon Ranch Pasta– combines chicken, pasta, ranch seasoning, crumbled bacon, and cheese in a tasty dish! Using only a few simple ingredients, this casserole is quick, easy, and perfect for busy weeknights!

Salsa Verde Chicken Pasta– a one-skillet meal with a smoky kick from salsa verde. It’s cheesy, delicious, and a family favorite!

Lemon Spaghetti– the perfect pasta dish and only takes 20 minutes to make! The lemon sauce is light, refreshing, and so delicious!

Garlic Parmesan Spaghetti– a simple pasta dish that can be served as a side or main dish. You can make this easy spaghetti recipe in about 15 minutes, using just 5 ingredients!

 

Cheesy Mexican Chicken Spaghetti Casserole is a delightful twist on a classic family favorite. It’s the perfect dish to satisfy those hungry tummies and bring smiles to everyone’s faces around the dinner table. With its gooey cheese, tender chicken, and bold flavors, it will surely become a new go-to recipe in your household. So whip out that apron, gather your ingredients, and get ready to enjoy some cheesy goodness with your loved ones. Trust me, this dish will not disappoint! Be sure to leave a star rating and comment below if you give it a try!